Atletico Madrid have to score if they want to progress. This much we know. After that, how they will go about trying to score while keeping Barcelona's potent attack at bay is anyone's guess. There is a train of thought that suggest Simeone will attack from the start in an effort to unsettle and magnify Barcelona's soft underbelly. Concede a goal and that plan will prove fool-hardy and garner plenty of criticism. Only time will tell how one of the most intriguing tactical battles of this year's Champions League will pan out.
Location: Vicente Calderon, Madrid, Spain
Kick-off time: 19:45 PM GMT, 14:45 Eastern, 11:45 Pacific
SB Nation OPPOSITION Blog: Barca Blaugranas
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Available streaming: NBC Sports Live Extra
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Atletico Madrid squad
Jan Oblak, Miguel Angel Moyá, Diego Godín, Stefan Savic, Lucas Hernandez, Filipe Luis, Juanfran, Jesus Gámez, Matias Kranevitter, Augusto Fernandez, Gabi, Koke, Saúl Niguez, Thomas Partey, Óliver Torres, Yannick Ferreira Carrasco, Angel Correa, Antoine Griezmann, Luciano Vietto.
Marc-André ter Stegen, Claudio Bravo, Jordi Masip, Douglas Pereira, Gerard Piqué, Dani Alves, Javier Mascherano, Marc Bartra, Jordi Alba, Adriano Correia, Ivan Rakitic, Sergio Busquets, Arda Turan, Andrés Iniesta, Sergi Roberto, Luis Suárez, Lionel Messi, Neymar Jr, Munir El-Haddadi